2019
Asada, H., Tomiyasu, H., Goto-Koshino, Y., Ohno, K., Tsujimoto, H.
Effect of a two-base insertion mutation of the TP53 gene on expression of p53 protein in canine histiocytic sarcoma cells. Am J Vet Res 2019;80 680-688.
Asada, H., Tomiyasu, H., Uchikai, T., Ishihara, G., Goto-Koshino, Y., Ohno, K., Tsujimoto, H.
Comprehensive analysis of miRNA and protein profiles within exosomes derived from canine lymphoid tumour cell lines. PLoS One 2019;14 e0208567
Kimura, H., Imura, Y.K., Tomiyasu, H., Mihara, T., Kaji, N., Ohno, K., Unno, T., Tanahashi, Y., Jan, T.R., Tsubone, H., Ozaki, H., Hori, M.
Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine. Sci. Rep. 2019;9 5887
Son, N.V., Uchida, K., Thongtharb, A., Chambers, J.K., Kishimoto, T.E., Tomiyasu, H., Ohmi, A., Tsujimoto, H., Nakayama, H.
Establishment of cell line and in vivo mouse model of canine Langerhans cell histiocytosis. Vet. Comp. Oncol. 2019 in press
Asada, H., Tomiaysu H., Okada, K., Chambers, J.K., Goto-Koshino, Y., Uchida, K., Kagawa, Y., Ohno, K., Tsujimoto, H.
Clinical significance of the two-base insertion mutation in the TP53 gene in canine histiocytic sarcoma. Res. Vet. Sci. 2019;124 57-60
Asada, H., Ichii, O., Tomiaysu H., Uchida, K., Chambers, J.K., Goto-Koshino, Y., Ohno, K., Kon, Y., Tsujimoto, H.
The intratumor heterogeneity of TP53 gene mutations in canine histiocytic sarcoma. J. Vet. Med. Sci. 2019;81 353-356
2018
Matsumoto, I., Nakashima, K., Goto-Koshino, Y., Chambers, J.K., Tsujimoto, H., Nakayama, H., Uchida, K.
Immunohistochemial Profiling of Canine Intestinal T-Cell Lymphomas Vet. Pathol. 2019;56 50-60.
Tomiyasu, H., Doi, A., Chambers, J.K., Goto-Koshino, Y., Ohmi, A., Ohno, K., Tsujimoto, H.
Clinical and clinicopathological characteristics of acute lymphoblastic leukaemia in six cats. J. Small Anim. Pract. 2018;59 742-746.
Motegi, T., Tomiyasu, H., Goto-Koshino, Y., Takahashi, M., Hiyoshi-Kanemoto, S., Fujino, Y., Ohno, K., Tsujimoto, H.
Prognostic value of CD44 variant isoform expression in dogs with multicentric high-grade B-cell lymphoma. Am. J. Vet. Res. 2018;79 961-969.
Maeda, S.*, Tomiyasu, H.*, Tsuboi, M., Inoue, A., Ishihara, G., Uchikai, T., Chambers, J.K., Uchida, K., Yonezawa, T., Matsuki, N. *Co-first authors
Comprehensive gene expression analysis of canine invasive urothelial bladder carcinoma by RNA-Seq. BMC Cancer 2018;18 472.
Matsumoto, I., Uchida, K., Nakashima, K., Goto-Koshino, Y., Chambers, J.K., Tsujimoto, H., Nakayama, H.
Pathological features of intestinal T-cell lymphoma in Shiba dogs in Japan. Vet. Comp. Oncol. 2018;16 417-423.
Sato, M., Mochizuki, H., Goto-Koshino, Y., Fujiwara-Igarashi, A., Takahashi, M., Ohno, K., Tsujimoto, H.
Prognostic significance of hypermethylation of death-associated protein kinase (DAPK) gene CpG island in dogs with high-grade B-cell lymphoma. Vet. Comp. Oncol. 2018;16:409-415.
Matsumoto, I., Uchida, K., Nakashima, K., Hiyoshi, S., Chambers, J.K., Tsujimoto, H., Nakayama, H.
IgA Antibodies Against Gliadin and Tissue Transglutaminase in Dogs With Chronic Enteritis and Intestinal T-Cell Lymphoma. Vet. Pathol. 2018;55:98-107.
2017
Suenaga, M., Tomiyasu, H., Watanabe, M., Ogawa, K., Motegi, T., Goto-Koshino, Y., Ohno, K., Sugano, S., Skorupski, K.A., Tsujimoto, H.
Comprehensive analysis of gene expression profiles reveals novel candidates of chemotherapy resistant factors in canine lymphoma. Vet. J. 2017;228 18-21.
Asada, H., Tsuboi, M., Chambers, J.K., Uchida, K., Tomiyasu, H., Goto-Koshino, Y., Ohno, K., Tsujimoto, H.
A 2-base insertion in exon 5 is a common mutation of the TP53 gene in dogs with histiocytic sarcoma. J. Vet. Med. Sci. 2017;79(10) 1721-1726.
Ohmi, A., Ohno, K., Uchida. K., Goto-Koshino Y., Tomiyasu, H., Kanemoto, H., Fukushima, K., Tsujimoto, H.
Significance of clonal rearrangements of lymphocyte antigen receptor genes on the prognosis of chronic enteropathy in 22 Shiba dogs. J. Vet. Med. Sci. 2017;79(9) 1578-1584.
Yamazaki, H., Miura, N., Lai, Y.C., Takahashi, M., Goto-Koshino, Y., Yasuyuki, M., Nakaichi, M., Tsujimoto, H., Setoguchi, A., Endo, Y.
Effects of toceranib phosphate (Palladia) monotherapy on multidrug resistant lymphoma in dogs. J. Vet. Med. Sci. 2017;79:1225-1229.
Hara, K., Iio, A., Asahina, R., Takahashi, M., Mori, T., Nishida, H., Kamishina, H., Sakai, H., Kitoh, K., Mizuno, T., Tsujimoto, H., Maeda, S.
Characterization of a novel canine T-cell line established from a dog with cutaneous T-cell lymphoma. J. Dermatol. Sci. 2017;88:254-256.
Yoshino, Y., Chambers, J.K., Nakamori, T., Goto-Koshino, Y., Nishigaki, K., Tsujimoto, H., Matsuki, N., Nakayama, H., Uchida, K.
Primary cerebellar lymphoma with Hodgkin lymphoma-like morphology in a cat. J. Vet. Diagn. Invest. 2017;29:707-710.
Ohmura, S., Leipig, M., Schöpper, I., Hergt, F., Weber, K., Rütgen, B.C., Tsujimoto, H., Hermanns, W., Hirschberger, J.
2016
Scott, M.C.*, Tomiyasu, H.*, Garbe, J.R., Cornax, I., Amaya, C., O'Sullivan, M.G., Subramanian, S., Bryan, B.A., Modiano, J.F. *Co-first authors
Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior. Dis. Model. Mech. 2016;9(12) 1435-1444.
Weiskopf, K., Anderson, K.L., Ito, D., Schnorr, P.J., Tomiyasu, H., Ring, A.M., Bloink, K., Efe, J., Rue, S., Lowery, D., Barkal, A., Prohaska, S., McKenna, K.M., Cornax, I., O'Brien, T.D., O'Sullivan, M.G., Weissman, I.L., Modiano, J.F.
Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20. Cancer Immunol. Res. 2016;4(12) 1072-1087.
Mochizuki, H., Fujiwara-Igarashi, A., Sato, M., Goto-Koshino, Y., Ohno, K., Tsujimoto, H.
Genetic and epigenetic aberrations of p16 in feline primary neoplastic diseases and tumor cell lines of lymphoid and non-lymphoid origins. Vet. J. 2017;219:27-33.
Fujiwara-Igarashi, A., Tomiyasu, H., Igarashi, H., Yu, Y., Gogo-Koshino, Y., Ohno, K., Tsujimoto, H.
Regulation of p16 gene expression by histone H3 acetylation in canine lymphoid tumor cell lines. Jpn. J. Vet. Res. 2016;64:257-263.
Kato, D., Takahashi, M., Harada, T., Tsuboi, M., Uchida, K., Fukushima, K., Kanemoto, H., Fujino, Y., Ohno, K., Nakayama, H., Tsujimoto, H.
Intranuclear inclusions in a dog with B-cell leukemia. Vet. Clin. Pathol. 2016;45:579-583.
Roode, S.C., Rotroff, D., Richards, K.L., Moore, P., Motsinger-Reif, A., Okamura, Y., Mizuno, T., Tsujimoto, H., Suter, S.E., Breen, M.
Comprehensive genomic characterization of five canine lymphoid tumor cell lines. BMC Vet. Res. 2016;12:207.87.
Sato, M., Yamazaki, J., Goto-Koshino, Y., Setoguchi, A., Takahashi, M., Baba, K., Fujino, Y., Ohno, K., Tsujimoto, H.
Minimal residual disease in canine lymphoma: An objective marker to assess tumour cell burden in remission. Vet. J. 2016;215:38-42.
Mizutani, N., Goto-Koshino, Y., Takahashi, M., Uchida, K., Tsujimoto, H.
Clinical and histopathological evaluation of 16 dogs with T-zone lymphoma. J. Vet. Med. Sci. 2016;78:1237-44.
Mizutani, N., Goto-Koshino, Y., Tsuboi, M., Kagawa, Y., Ohno, K., Uchida, K., Tsujimoto, H.
Evaluation of CD25-positive cells in relation to the subtypes and prognoses in various lymphoid tumours in dogs. Vet. Immunol. Immunopathol. 2016;173:39-43.
Koshino, A., Goto-Koshino, Y., Setoguchi, A., Ohno, K., Tsujimoto, H.
Maeda, S., Ohno, K., Fujiwara-Igarashi, A., Uchida, K., Tsujimoto, H.
2015
Scott, M.C., Sarver, A.L., Tomiyasu, H., Cornax, I, VamEtten, J., Varshney, J., O’Sullivan, M.G., Subramanian, S. and Modiano, J.F.
Aberrant RB-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma. J. Biol. Chem. 2015;290(47) 28070-28083.
Tomiyasu, H. and Tsujimoto H. Comparative Aspects of Molecular Mechanisms of Drug Resistance through ABC Transporters and Other Related Molecules in Canine Lymphoma. Vet. Sci. 2015;2(3) 185-205.
Asada, H., Tomiyasu, H., Goto-Koshino, Y., Fujino, Y., Ohno K. and Tsujimoto, H. Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lies. J. Vet. Med. Sci. 2015;77(6) 677-684.
Fujiwara-Igarashi, A., Igarashi, H., Mizutani, N., Goto-Koshino, Y., Takahashi, M., Ohno, K., Tsujimoto, H.
Goto-Koshino, Y., Mochizuki, H., Sato, M., Nakashima, K., Hiyoshi, S., Fujiwara-Igarashi, A., Maeda, S., Nakamura, K., Uchida, K., Fujino, Y., Ohno, K., Tsujimoto, H.